Scientific publications
deCODE is widely recognized as the world leader in the discovery of genes contributing to risk of common diseases. deCODE has also led the way in publishing its discoveries, a commitment that not only drives ongoing research but also enables independent researchers from around the globe to validate the company’s discoveries.
- deCODE´s discovery of variants on chromosome 15q24 associated with increased risk of exfoliation glaucoma, published in September 2007, has been replicated in two published studies on Caucasians. A list of key publications includes: Gudmar Thorleifsson, et al. Confer Susceptibility to Exfoliation Glaucoma Common Sequence Variants in the LOXL1. Science 317, 1397 (2007) http://www.sciencemag.org/cgi/reprint/317/5843/1397.pdf).
- Fingert J.H. Correspondence: LOXL1 Mutations Are Associated with Exfoliation Syndrome in Patients from the Midwestern United States. Am. J. Opht. 2007; 144, 974-975
- Alex W Hewitt. Ancestral LOXL1 variants are associated with pseudoexfoliation in Caucasian Australians but with markedly lower penetrance than in Nordic people. Human Molecular Genetics Advance Access published November 23, 2007
For a complete list of relevant publications, click here.